Tips For Botox From a Doctor
Allergan, the maker of Botox or botulinum toxin, was an original Dermatology / Ophthalmology product company. Began developmemt of Botox as an experimental drug for more than three decades in the 1970s. It Opthalmological researchers tested in monkeys with strabismus (eye muscle disorder known as squint-eyed or wall) with amazing healing results. They have since tried and extending its uses to include cosmetic facial applications that were granted in 2002. This is the application that Botox Cosmetic has exploded to the scene of America and worldwide.
Manufacturing Botox is an interesting story. In the beginning, was conducted under the strict supervision of the U.S. Military because it was a poisonous drug. Since then, comes in a secret location in the U.S. and then sent for bottling in Ireland. If this story is really true, I do not know, but certainly adds to the mystique of the drug. It is certainly the most expensive drug in the world if you break your pricing structure. After 5 nanograms of volume in each bottle sold nearly $ 500 per bottle for suppliers, which makes its worth over 1 trillion dollars per pound!
Botox or botulinum toxin, is produced from anaerobic (oxygen), bacterial cultures to create a toxin. The toxin is composed of seven chapters, called A, B, C, D, E, F, G. Each chapter can block the release of the neurotransmitter, acetylcholine, from nerve synapses resulting in temporary muscle paralysis. (no power to the muscle so to speak) The different serotypes have different durations of action before it disappears. Serotype A lasts about three to four months, while serotype F lasts a few weeks. This is why you see in the bottle and Botox in their ads, botulinum toxin A, a serotype that lasts longer.
toxin Botox is placed in small vials of 100 units as fodder (dry) powder. But what does the 100 units? That means how many units are needed to kill 100 mice. Each vial contains then one hundred mice units or 100 units for short. Initially, Allergan used 25 nanograms of the toxin to kill 100 mice. However, it has been learned to the improvement of manufacturing technology and less need to do the same job and the quantity per bottle was reduced to 5 nanograms. This is of great importance because Botox is a drug that requires repeated injections over time to maintain its effects. The repeated use of lower doses reduce the likelihood that patients may develop resistance or immunity. And despite what is often touted, select a few people have a natural immunity to Botox and other developed resistance to some of its effects over time.
As a cosmetic treatment, Botox is what I call a “northern” treatment “. It is excellent in controlling undesirable expressions around the eyes and forehead. This northern area of the face probably accounts for the vast majority of its cosmetic use as it provides real results that sometimes the surgery can not rival. It can also be used in the southern part of the face around the mouth. However, its effectiveness in this area is diminished as surgical treatments are often more effective and more than Botox plays an auxiliary role as a complement to other treatments.
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